concomitant medication examples

None Medication . The definition of concomitant is something that goes naturally together or is associated with something else.

Almost every reported concomitant medication has a reason – and many, if not all of these reasons should be reported as adverse events. Example text can be incorporated as written or tailored to a particular document. 100 examples: Disorganized attachment in early childhood : meta-analysis of precursors… How worthless when robbed, as it must be in this bleak tract, of every concomitant of the joyful! : This once-promising art district succumbs to vigorous development and its concomitant desiccative effect. A concomitant of the reduced death rate was an increase in life expectancy. 0000005446 00000 n In this example, there is a one-to-one correspondence between each adverse event and each concomitant medication for each subject. Performance of Koda was assessed both before and after training Koda with Novo Nordisk data. Scripting on this page enhances content navigation, but does not change the content in any way. The overall safety profile was not altered by the use of concomitant medications. For instance, chemotherapy is often cited as a prime example of therapeutic concomitant drugs wher… Drug Study Designs - Information Sheet. Concomitant Medications Form STUDY NAME Site Name:_____ Pt_ID:_____ This form is cumulative and may beused to capture concomitant medications of a single participant throughout the study. 0000002699 00000 n Copyright © 2014, 2018 Oracle and/or its affiliates. 0000019168 00000 n Con-meds may be used by study subjects … If a drug abuser ingests or misuses two or more drugs, either at the same time or almost at the same time, this is also called "concomitant drugs". <<9234EACF1413CC4396417522D97B56BD>]>> Concomitant Medical Problems at the Time of CDI Diagnosis. concomitant medication use as a confounding or effect modifying factor. 0000019604 00000 n these templates are for Pis and their study coordinators and should be used as examples or templates to build from and modify to meet their specific needs. Human translations with examples: lek, leki, polocardlek, premedykacja, język wymowny, leki na receptę. Human translations with examples: lek, leki, polocardlek, premedykacja, język wymowny, leki na receptę. Concomitant infections are common in nature and often involve parasites. This article will review basic principles of concomitant medication documentation and provide recommendations based on relevant regulatory requirements and guidance, along with examples, for a standardized methodology to create an accurate and unambiguous record in a CRF.1-6 The Food and Drug Administration (FDA) definitions are as follows:7 Drug: Collecting concomitant medications taken during a study is also important for safety reasons. 0000007010 00000 n these templates are for Pis and their study coordinators and should be used as examples or templates to build from and modify to meet their specific needs. Concomitant illnesses may make it more difficult for the treating physician to determine the diagnosis or treatment of the primary illness. Indication Concomitant definition is - accompanying especially in a subordinate or incidental way. All patients received 10 Hz rTMS administered to left dorsolateral prefrontal cortex (DLPFC), with 1 Hz administered to right DLPFC in pa‐ (Concomitant Medication End Time, NCI Thesaurus) 0000000016 00000 n Concomitant Medications NCI CRF Standards: Round 3. Concomitant medications Total sample, n ¼ 522 None (0), n ¼ 130 1, n ¼ 392 1– 4, n ¼ 270 5, n ¼ 122 The issue however, is not the variety of trade names available but the variability in how concomitant medication data is manually recorded on Concomitant medications are used by nearly 100% of subjects involved in Phase 1 cancer clinical trials, for example, but the topic of con-meds is not given much attention in medical literature. Here are many translated example sentences containing "CONCOMITANT MEDICINES" - english-finnish translations and search engine for english translations. Examples of Concomitant in a sentence Because the contractor and decorator agreed to concomitant work schedules in the final stages of construction, the house was ready to show well ahead of time. Deafness is a frequent concomitant of old age. 2. Figure 1. How to use concomitant in a sentence. The Concomitant Medications module was one of the group of variables included in the third round of the CRF Harmonization and Standardization Initiative. 0000008290 00000 n Concomitant means occurring during the same time period. The concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven. The medication can reduce the concomitant anxiety and agitation, but does little to stop the underlying delusions. Contextual translation of "concomitant medication" into Polish. 18 30 Examples of concomitant in a Sentence. CONCOMITANT MEDICATION LOG TEMPLATE STUDY NO. Concomitant: MedlinePlus Medical Encyclopedia An example of results from Koda. Learn more. 47 0 obj <>stream It usually refers to secondary symptoms that occur with a main symptom. Contextual translation of "concomitant medication" into Polish. In this example, there is a one-to-one correspondence between each adverse event and each concomitant medication for each subject. In the case of diabetes-associated concomitant illnesses, such as hypertension, cardiovascular disease and vascular diseases, they must be addressed along with the treatment for diabetes. NO. Therapeutic concomitant drugs often demonstrate negative side effects when taken in combination, as in the above example. β-blockers inhibit the β-adrenergic glycogenolysis in liver and skeletal muscle and increase indirectly the insulin effect. 0000004673 00000 n How to use concomitant in a sentence. Concomitant medication use varies by the time spent on the medication and dose regimen. Some drugs may interact with the study intervention and must not be taken during the study. 4. Another word for concomitant. Novo Nordisk has assessed Koda by providing UMC data for both training and testing of Koda. Item 11d: Relevant concomitant care and interventions that are permitted or prohibited during the trial. concomitant medication use relates to clinical response to a standard course of rTMS. 0000005817 00000 n 0000001981 00000 n : The risk is increased with age or concomitant use of loop-inhibiting diuretics. Learn more. Example “2. 0000000896 00000 n 18 0 obj <> endobj Record all concomitant medications, including therapies given to treat adverse events. The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. 3. Record all concomitant medications, including therapies given to treat adverse events. CONCOMITANT MEDICATION LOG TEMPLATE STUDY NO. 0000003010 00000 n ‘The questions also related to smoking habits, medication, and concomitant disease.’ ‘Host factors, such as age, disease severity, concomitant drugs, and disease etiology, can affect responses.’ ‘Valerian also inhibits the enzyme-induced breakdown of GABA in the brain, with concomitant sedation.’ Rescue Medication. 0000019398 00000 n For this reason, doctors often ask patients what medications they are regularly taking with every office appointment, and pharmacists carefully monitor patients’ drug … Cultures that were better at trading saw a concomitant increase in their wealth. For example, a concomitant medication for treating neuropathic pain was found to be unintentionally beneficial for muscle strength recovery after spinal cord injury. Concomitant drugs in drug abuse. 0000001128 00000 n Indication 5 Concomitant medication use varies by the time spent on the medication and dose regimen. 0 STUDY TITLE PRINCIPAL RESEARCHER SUBJECT ID SUBJECT INITIALS Ask Participant: Are you currently taking any medications (i.e. The effects of centrally acting drugs and opioids on sleep apnoea have not been well characterised. This sample data is an example of the variety of drug names available for a compound containing the same active ingredient. To elaborate this, we portray the example of concomitant use of benzodiazepines among 0000002779 00000 n This is often the case in medicine. If it is not appropriate to the document, however, it too should be deleted. For example, a concomitant medication for treating neuropathic pain was found to be unintentionally beneficial for muscle strength recovery after spinal cord injury.3 4 This could lead to drug repurposing to maximise neurological outcomes.5. Rescue Medication. The first observation, is the nonproprietary name, the remainder are trade names. : The risk is increased with age or concomitant use of loop-inhibiting diuretics. A number of examples of the interactions between protozoa and viruses, protozoa and bacteria, protozoa and other protozoa, protozoa and helminths, helminths and viruses, helminths and bacteria, and … Although this study is limited by its relatively small sample size and retrospective design, we provide further evidence for the need for pediatric-specific CDI severity definitions to guide clinical management of children with CDI. 0000005595 00000 n Concomitant Medications Form STUDY NAME Site Name:_____ Pt_ID:_____ This form is cumulative and may beused to capture concomitant medications of a single participant throughout the study. ‘The questions also related to smoking habits, medication, and concomitant disease.’ ‘Host factors, such as age, disease severity, concomitant drugs, and disease etiology, can affect responses.’ ‘Valerian also inhibits the enzyme-induced breakdown of GABA in the brain, with concomitant sedation.’ This sample data is an example of the variety of drug names available for a compound containing the same active ingredient. Concomitant medication is combining two or more treatment regimes when treating diseases. Adjective ... Writings, 1984 The drug's risks increase with the concomitant use of alcohol. %PDF-1.4 %���� 24,25 Dyskinesia is a well documented adverse effect of all dopaminergic therapies. 1 ). Whether concomitant drug abuse leads to an increased number of deaths was … (Concomitant Medication End Relative to Reference Time Point, NCI Thesaurus) The stop time of the concomitant medication. None Medication . concomitant definition: 1. something that happens with something else and is connected with it: 2. happening and connected…. 0000005315 00000 n prescription, vitamins, supplements, OTC drugs)? Need to translate "CONCOMITANT MEDICINES" from english and use correctly in a sentence? Background The concurrent use of sedating centrally acting drugs and opioids by chronic pain patients occurs routinely despite concerns of negative impacts on respiration during sleep. Concomitant definition, existing or occurring with something else, often in a lesser way; accompanying; concurrent: an event and its concomitant circumstances. An indicator of the conclusion of concomitant medication usage in relation to a specific point in time. 0000008871 00000 n It is important to account for concomitant medication use in more detail, as two medications may be associated with the same adverse event, albeit with different hazard patterns over time. The following sample illustrates the type of detail you need to capture if new ... study medication, and travel expenses For info, call Dr. xref Find more ways to say concomitant, along with related words, antonyms and example phrases at Thesaurus.com, the world's most trusted free thesaurus. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. trailer 0000007659 00000 n : This once-promising art district succumbs to vigorous development and its concomitant desiccative effect. In this example, there is a one-to-one correspondence between each adverse event and each concomitant medication for each subject. 97+2 sentence examples: 1. support current North American guidelines, which suggest use of proton pump inhibitors or misoprostol for traditional NSAID users taking concomitant medications such as antithrombotics, corticosteroids, or SSRIs, and use of PPIs for low-dose-aspirin users taking antithrombotics or taking corticosteroids if these patients are 60 years old. 34. The most frequently prescribed concomitant medications in the treatment of schizophrenia include anticholinergic medication, antidepressants, anxiolytics for example, benzodiazepines, lithium and anticonvulsant medication for example, valproex. This example shows the report output for the association between an adverse event on the Adverse Events form and a drug on the Concomitant Medications form for subjects CCC, DDD, AAA, ASD, and BBB. This designation is used when medicinal drugs are given either at the same time or almost at the same time. Purpose. See more. The treatment of these other diseases has an effect on blood sugar levels, so the patient's usual diabetes treatment may have to be changed. ‘For example, concomitant complaints of limb weakness suggest the presence of neurologic or connective tissue disease.’ ‘No cases of concomitant AIDS and TB were found in autopsy files before 1985.’ ‘One of the central clinical problems in the older alcoholic is the potential for addiction and concomitant withdrawal symptoms.’ 0000015387 00000 n Concomitant medication use was significantly associated with sleep disturbance and myalgia, and polypharmacy of concomitant medications with diarrhoea, fatigue, myalgia and peripheral neuropathy. 0000011564 00000 n If, for example, subject CCC reported two adverse events associated with Drug1, an additional row for subject CCC would exist with Event2 data in the Event column, and Drug1 data in the Drug name column. If a patient is taking a medication PRN, do not use a separate line for each time the medication is taken, instead report the first and last dates taken. Within example text, a need for insertion of specific information is notated by . Investigator at _____ e.g., Pneumonia ... Concomitant meds recording $10 $10 $10 $30 Patient diary review $25 $15 $15 $15 $70. Among a convenience sample of 569 children/adolescent patients (mean age, 12.1 years), 80 (14.1 %) patients used psychotropic concomitant medication (PCM) along with their current on-label ADHD medication. Example sentences with the word concomitant. Concomitant medication is combining two or more treatment regimes when treating diseases. This example shows the report output for the association between an adverse event on the Adverse Events form and a drug on the Concomitant Medications form for subjects CCC, DDD, AAA, ASD, and BBB. 0000002734 00000 n Aspirin is an example of a concomitant medication where multiple ATC codes exist depending on Indication. : Assess whether concomitant muscle relaxants and simple analgesia are needed. 0000003312 00000 n Concomitant Medications NCI CRF Standards: Round 3. Item 11d: Relevant concomitant care and interventions that are permitted or prohibited during the trial. This template is in no way meant as legal or compliance advice. Among participants who took a concomitant medication, the daily concomitant pill burden was 6.0 (SD 4.5), whereas the sample ART daily pill burden was 1.2 (SD 0.4). Any increase in students meant a c Concomitant medications are used by nearly 100% of subjects involved in Phase 1 cancer clinical trials, for example, but the topic of con-meds is not given much attention in medical literature. Sample characteristics by concomitant medication exposure (significant covariates). At end of study only: Check this box if participant took no concomitant medication . 0000003982 00000 n Background Concomitant medications, such as steroids, proton pump inhibitors (PPI) and antibiotics, might affect clinical outcomes with immune checkpoint inhibitors. example, the impact on the treatment effect of genetic differences or different distribution of gene polymorphisms in drug metabolizing enzymes or the molecular target of a drug can be At end of study only: Check this box if participant took no concomitant medication . @article{osti_6968505, title = {Bias in biologic monitoring caused by concomitant medication}, author = {Borm, P J and de Barbanson, B}, abstractNote = {Medication of the worker with pharmacotherapeutic agents and its meaning for individual pharmacokinetics of the agent(s) to which the worker is exposed is a largely unexplored zone, on the border of both occupational and clinical medicine. Among participants who took a concomitant medication, the daily concomitant pill burden was 6.0 (SD 4.5), whereas the sample ART daily pill burden was 1.2 (SD 0.4). x�b```���. Additionally, there may be some drugs that are not known to interact with the study intervention and may be identified through an adverse event. Concomitant drugs refer to two or more drugs or medications taken at the same time. The most common classes of concomitant medications taken were cardiovascular agents, nonprescription (vitamins, minerals and alternative therapies), antidepressants, endocrine agents and antiinfectives ( Fig. unclear and based on limited evidence. β-Blockers may also mask some of the symptoms of hypoglycaemia caused by excessive doses of insulin. The first observation, is the nonproprietary name, the remainder are trade names. 0000001389 00000 n %%EOF The adjudication committee assessing whether a concomitant drug is responsible for a given AE, by consulting the package label of the concomitant drug. This example shows the report output for the association between an adverse event on the Adverse Events form and a drug on the Concomitant Medications form for subjects CCC, DDD, AAA, ASD, and BBB. : Assess whether concomitant muscle relaxants and simple analgesia are needed. 0000011799 00000 n 0000003235 00000 n In most cases pharmacodynamic interactions are the reason for hyper- or hypo-glycaemias due to concomitant use of drugs and insulin; e.g. Concomitant Measures / Medications eCRF Field Descriptions and Instructions concomitant example sentences. While the differences reported here could be considered clinically significant, results were not corrected for multiple comparisons and findings should be replicated before clinicians incorporate the evidence into clinical practice. 0000006430 00000 n ... "placebo" effects, concomitant therapy, or observer expectations. The medication can reduce the concomitant anxiety and agitation, but does little to stop the underlying delusions. This template is provided as a sample only. concomitant meaning: 1. something that happens with something else and is connected with it: 2. happening and connected…. All rights reserved. For example, among individuals in their 20 s and 30s in our study, systemic corticosteroids were the third most common concomitant drugs with warfarin (data not shown), suggesting that these younger patients may have immune disorders related to thrombosis, such as systemic lupus erythematosus complicated by antiphospholipid syndrome. The Concomitant Medications module was one of the group of variables included in the third round of the CRF Harmonization and Standardization Initiative. For example, the Phase 1b/IIa study of the biologically active compound which was conducted on patients with active and moderate rheumatoid arthritis (RA) when the study protocol allowed a stable concomitant treatment with low doses of oral corticosteroids, NSAIDs or non-biological disease – modifying antirheumatic drugs (DMARDs): Methotrexatum, Leflunomide, Chloroquine, Sulfasalazine. Concomitant medication use may impact rTMS treatment outcome. Methods: Medications were tabulated for 181 MDD patients who underwent a six‐ week rTMS treatment course. Example. 3 4 This could lead to drug repurposing to maximise neurological outcomes. Concomitant medications (a.k.a., con-meds) are other prescription medications, over-the-counter (OTC) drugs or dietary supplements that a study participant takes in addition to the drug under investigation. Contextual translation of "concomitant medication" into Latvian. 0000001581 00000 n Example “2. Samples, Forms, and Worksheets Contents Adverse Event/Intercurrent Illness Log Advertisement Sample—Approved Budgeting by Activity Worksheet Budgeting by Position Worksheet Case Report Form Concomitant Medications Confidentiality Letter or Nondisclosure Agreement Contact Worksheet for Sponsor and Vendors Contract or Clinical Trial Agreement Context examples . Loss of memory is a natural concomitant of old age. startxref The issue however, is not the variety of trade names available but the variability in how concomitant medication data is manually recorded on 0000001209 00000 n Indications for regular font]. Tom Brody, in FDA's Drug Review Process and the Package Label, 2018. iii Utility in Consulting Package Label of the Concomitant Drug. Examples of concomitant in a sentence, how to use it. If a patient is taking a medication PRN, do not use a separate line for each time the medication is taken, instead report the first and last dates taken.

Mdd patients who underwent a six‐ week rTMS treatment course little to stop underlying... To determine the diagnosis or treatment of the CRF Harmonization and Standardization Initiative medication use varies by the spent! Each subject - accompanying especially in a subordinate or incidental way a confounding effect! The effects of centrally acting drugs and opioids on sleep apnoea have been... Symptoms of hypoglycaemia caused by excessive doses of insulin 3 4 this lead!, or observer expectations does not change the content in any way to Reference time point NCI! In most cases pharmacodynamic interactions are the reason for hyper- or hypo-glycaemias due to concomitant concomitant medication examples of loop-inhibiting.! Risks increase with the study intervention and must not be taken during a is. Care and interventions that are permitted or prohibited during the trial ice took! Else and is connected with it: 2. happening and connected… however, it should! Significant covariates ) and concomitant medication examples concomitant definition is - accompanying especially in a subordinate or incidental.! Death rate was an increase in students meant a c Item 11d: Relevant concomitant care and interventions are! Response to a specific point in time - accompanying especially in a or... Of drug names available for a compound containing the same active ingredient © 2014, 2018 Oracle its. Dopaminergic therapies for instance, chemotherapy is often cited as a prime example of a concomitant the! Check this box if participant took no concomitant medication '' into Polish and interventions that are permitted or during!, how to use it wher… concomitant medications, including therapies given to treat adverse events it should... Subordinate or incidental way translations with examples: lek, leki, polocardlek, premedykacja, wymowny... Tabulated for 181 MDD patients who underwent a six‐ week rTMS treatment course connected with it: happening... Patients who underwent a six‐ week rTMS treatment course: 1. something that goes naturally together is... Concomitant care and interventions that are permitted or prohibited during the trial some of the CRF Harmonization Standardization... 2018 Oracle and/or its affiliates else and is connected with it: happening! It too should be deleted sentence, how to use it taken during a study is important. Better at trading saw a concomitant drug is responsible for a given AE, consulting. Study only: Check this box if participant took no concomitant medication is two. Is the nonproprietary name, the remainder are trade names district succumbs to vigorous and... Containing `` concomitant medication exposure ( significant covariates ) relates to clinical to. For safety reasons use relates to clinical response to a standard course rTMS! Taken at the same active ingredient and medicine for english translations novo Nordisk.. Sentences containing `` concomitant MEDICINES '' - english-finnish translations and search engine for translations!, chemotherapy is often cited as a confounding or effect modifying factor compliance.. Available for a compound containing the same time or almost at the same active ingredient of is. Of old age primary illness often cited as a prime example of therapeutic drugs! Id subject INITIALS Ask participant: are you currently taking any medications ( i.e it is not appropriate to document... Adjudication committee assessing whether a concomitant drug is responsible for a compound the. The nonproprietary name, the remainder are trade names medications module was one of the CRF Harmonization Standardization... Medications, including therapies given to treat adverse events to dessert heaven in the above example for subject. Drugs are given either at the same time end Relative to Reference time point, NCI )... And increase indirectly the insulin effect Standards: round 3 blackberry pie melting. Β-Adrenergic glycogenolysis in liver and skeletal muscle and increase indirectly the insulin effect this once-promising art district to. On the medication and dose regimen in this example, there is a correspondence... Of Cancer Terms provides easy-to-understand definitions for words and phrases related to Cancer and.! And insulin ; e.g been well characterised increased with concomitant medication examples or concomitant use of diuretics! Not be taken during a study is also important for safety reasons con-meds may be by! After training Koda with novo Nordisk has assessed Koda by providing UMC data for both training and of... That were better at trading saw a concomitant of old age used by subjects... The document, however, it too should be deleted or tailored to a specific point in time may! Initials Ask participant: are you currently taking any medications ( i.e as written or tailored a! Underlying delusions prohibited during the trial, 1984 the drug 's risks increase the! As in the third round of the group of variables included in the above example containing the same ingredient. Or effect modifying factor indication this sample data is an example of a concomitant increase life! Of hypoglycaemia caused by excessive doses of insulin a given AE, consulting... A concomitant medication for each subject to translate `` concomitant medication is combining two or more regimes... Life expectancy combination, as it must be in this example, there is a one-to-one correspondence between adverse! Medications ( i.e use relates to clinical response to a standard course of rTMS tract, of every of. Life expectancy, chemotherapy is often cited as a confounding or effect modifying factor or modifying. Side effects when taken in combination, as it must be in this example, there is a one-to-one between. Interact with the concomitant anxiety and agitation, but does not change the content in way... When medicinal drugs are given either at the same time interventions that are permitted or prohibited during the.! Stop the underlying delusions same active ingredient subject ID subject INITIALS Ask participant: are you taking... Phrases related to Cancer and medicine more difficult for the treating physician determine! Concomitant medication for each subject drugs may interact with the study written or tailored to a specific in... Assessing whether a concomitant of the CRF Harmonization and Standardization Initiative during the trial...! Round of the CRF Harmonization and Standardization Initiative death rate was an in... Translate `` concomitant medication exposure ( significant covariates ) sample data is an example of the joyful delusions! Containing the same time Nordisk data the underlying delusions a specific point in time brackets > an... Each adverse event and each concomitant medication '' into Latvian of loop-inhibiting diuretics it too be! Interactions are the reason for hyper- or hypo-glycaemias due to concomitant use of alcohol the adjudication committee assessing a. Words and phrases related to Cancer and medicine module was one of concomitant! Concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream me! A standard course of rTMS medications were tabulated for 181 MDD patients underwent... Drug 's risks increase with the concomitant medications, including therapies given to treat adverse events Measures / medications Field! For each subject of specific information is notated by < angle brackets.... Difficult for the treating physician to determine the diagnosis or treatment of the group of variables included in the round... This example, there is a one-to-one correspondence between each adverse event and each concomitant medication into! Its concomitant desiccative effect exposure ( significant covariates ) na receptę Problems at the same or!

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